Jow Forums Red-Pill University: Vaccines and Immunity

*** Introduction ***

The shilling and retardation in Jow Forums recently regarding vaccination has reached the point where the average user can't tell the shills and brainwashed NPC idiots from those that are educated (both formally and through informal journal research) when it comes to vaccines and immunity. The purpose of this course at Jow Forums Red-Pill University is to teach you the science of vaccines and immunity from a fact and evidenced-based perspective, broken down to Barney the faggot dinosaur levels of reading comprehension. Everything presented below is 100%, verifiably true, and anyone that argues otherwise is either willfully ignorant, woefully misinformed, or has a malicious agenda ... and unfortunately, most medically trained individuals--be they nurses, physicians, or researchers--fall into the first two categories.

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Other urls found in this thread:

ncbi.nlm.nih.gov/pubmed/11118387
ncbi.nlm.nih.gov/pubmed/22525386)
ncbi.nlm.nih.gov/pubmed/22423139)
ncbi.nlm.nih.gov/pubmed/23413420)
ncbi.nlm.nih.gov/pubmed/19879807)
ncbi.nlm.nih.gov/pubmed/19440239)
ncbi.nlm.nih.gov/pubmed/1450674)
amazon.com/Vaccines-Autoimmunity-Yehuda-Shoenfeld/dp/1118663438).
ncbi.nlm.nih.gov/pubmed/23338829)
ncbi.nlm.nih.gov/pubmed/22531966)
ncbi.nlm.nih.gov/pubmed/12793601)
ncbi.nlm.nih.gov/pmc/articles/PMC3170075/)
ncbi.nlm.nih.gov/pubmed/24763539)
ncbi.nlm.nih.gov/pmc/articles/PMC1448377/)
ncbi.nlm.nih.gov/pubmed/25428645)
ncbi.nlm.nih.gov/pubmed/19740540)
academic.oup.com/aje/article-abstract/11/3/576/63159?redirectedFrom=fulltext.
raisinghealthychildren.net
ncbi.nlm.nih.gov/pmc/articles/PMC5360569/)
sciencedirect.com/science/article/pii/S0162013411002212)
scirp.org/journal/PaperInformation.aspx?PaperID=22932)
ncbi.nlm.nih.gov/pubmed/15951359)
ncbi.nlm.nih.gov/pubmed/9824838)
ncbi.nlm.nih.gov/pubmed/25535199)
sciencedirect.com/science/article/pii/S0946672X17308763)
cdc.gov/mmwr/volumes/67/wr/mm6742a4.htm)
ncbi.nlm.nih.gov/pmc/articles/PMC2880100/)
ncbi.nlm.nih.gov/pubmed/1565228)
ncbi.nlm.nih.gov/pubmed/1884314)
sciencemag.org/news/2014/04/measles-outbreak-traced-fully-vaccinated-patient-first-time)
ncbi.nlm.nih.gov/pubmed/23932735)
twitter.com/SFWRedditGifs

*** PART 1 ***

How your immune system works, for dummies:

Humans have two types of immune systems, the innate and adaptive immune systems. We won't be discussing the innate system, because it doesn't apply to vaccination; it is non-specific, and has no immunological memory. The adaptive immune system is specific and has a memory, and is the system we will be focusing on.

ncbi.nlm.nih.gov/pubmed/11118387 is a non-Barney-style academic explation of the following:

The adaptive immune system breaks down into two primary mechanisms of response: type 1 (Th1) and type 2 (Th2) immunity.

Type 1 (Th1) immunity primarily involves phagocytic activity by killer T cells (CD8) which directly attack foreign, infected, or mutated (such as cancer) cells. T cell activation is tightly controlled and generally requires a very strong antigen activation signal, typically due to an acute infection. This is also generally known as "cell-mediated" immunity, and through its activation it also produces a simultaneous humoral response through helper T cells (CD4) (Th2). This process is both non-specific in that it will fuck up any cell that doesn't isn't properly flagged as "self", and specific in that it will encourage the humoral system to mount a large-scale precision response to whatever has pissed it off. Furthermore, this process creates an exponentially-growing positive feedback loop that can create a massive immune response very quickly, and creates both memory B and T cells.

Type 2 (Th2) immunity primarily involves humoral immunity, and is the standard immune response to mild antigen activation signals. This is regulated by helper T cells (CD4) and B cells (antibody generators). Outside of the presence of an antigen that the B cell has been taught to make antibodies for by helper T cells, new memory B cells will not be created, and during a Th2 response ONLY memory B cells will be created. Eventually, these cell lines will be reprogrammed or die off, explaining why humoral immunity fades over time, and cell-mediated immunity is generally life-long.

From that abstract: "Th1 cells also stimulate moderate levels of antibody production, whereas Th2 cells actively suppress phagocytosis. For most infections, save those caused by large eukaryotic pathogens, type 1 immunity is protective, whereas type 2 responses assist with the resolution of cell-mediated inflammation." In other words, in a primary Th2 response, the Th1 pathway is suppressed.

What does this mean? The more the immune system is trained to mount Th2 responses to infectious agents, the less the immune system is capable of mounting Th1 responses. Why is this important? The literature is packed with peer-reviewed research that conclusively proves that infection with childhood illnesses reduces cancer risks later in life. Why? The immune system is being actively trained to have strong Th1 responses to anything that looks weird. Failure to contract childhood illnesses leaves the body less equipped to deal with weird shit, and thus cancer is more likely to take root.

So ... wouldn't vaccination cause this same response? FUCK NO. NEVER. This is why understanding the immune system is critical to understanding the vaccine debate: vaccines inevitably cause ONLY a Th2 response by the immune system. The point of vaccines is to generate antibody-producing memory B cells, so the next time the immune system is presented with the antigen from the vaccine, antibodies can be produced. It is ABSOLUTELY CRITICAL to understand that this in no way protects the body in the same way as an acute, natural infection, and in no way prevents an acute infection from the source of the antigens if the humoral immune system gets overwhelmed. Should this happen, the vaccinated individual is less-equipped to handle the infection than an individual that is totally naive to the infectious agent, as Th1 immunity has been actively stunted and suppressed. Furthermore, even if the humoral (Th2) response is sufficient to stymie acute infection from a programmed antigen, the immune system of vaccinated individuals will be less able to mount an effective Th1 response to any infection that they body has not been programmed to recognize.

Vaccination does not strengthen the immune system, it directly and measurably weakens it. No other conclusion can be reached based on nothing more than what you would learn in a 200-level A&P or microbiology course, if you take a moment to consider the implications of what you're learning. More advanced courses simply reinforce this lesson with a more detailed understanding of why this occurs. While I've had that education, it is definitely beyond the scope of this course, and unnecessary for having a better understanding of the vaccine debate.

"user, that sounds like so much horseshit! There is no proof of this!"

Yes there is! The best example of this is the flu vaccine, which even the most strident pro-vaccination niggers recognize problems with. From the literature:

Children who were vaccinated against influenza were 3 times more likely to be hospitalized for influenza-related complications than children who did not receive an influenza vaccine (OR = 3.67). (ncbi.nlm.nih.gov/pubmed/22525386)

Children who received the influenza vaccine were 4 times more likely than children who received a placebo to develop acute respiratory illness from non-influenza respiratory virus infection (RR = 4.40). Influenza vaccine recipients were significantly more likely than placebo recipients to develop non-influenza respiratory infections from rhinoviruses, coxsackieviruses, and echoviruses (RR = 3.46). (ncbi.nlm.nih.gov/pubmed/22423139)

The current season’s influenza vaccine will not work in people who also received the previous season’s influenza vaccine. People who were vaccinated 2 years in a row were not protected against influenza. In fact, vaccine effectiveness was “negative 45%”. (ncbi.nlm.nih.gov/pubmed/23413420)

Annual vaccination against common strains of influenza reduces protective immunity against more dangerous strains of the disease. Annual vaccinations of young children against common influenza strains prevents them from acquiring more comprehensive immunity, leaving them unprotected against dangerous pandemic strains. (ncbi.nlm.nih.gov/pubmed/19879807)

Mice that were infected with a seasonal influenza virus survived exposure to a lethal influenza strain; vaccinated mice died. (ncbi.nlm.nih.gov/pubmed/19440239)

Adults with previous infections of influenza, measles, mumps, or chickenpox are less likely to develop malignant melanoma. Adults were significantly protected against malignant melanoma if they contracted influenza during the previous 5-year period (OR = 0.32). (ncbi.nlm.nih.gov/pubmed/1450674)

There are hundreds of peer-reviewed scientific journal articles that could be included in this list, and these being are provided just to demonstrate the point. Not only does vaccination not provide the same strength immunity as acute, natural infection, and not only does vaccination provide the same duration of immunity as acute, natural infection, but vaccination can demonstrably weaken the immune system against the very antigen-producing agents that they are supposed to protect against. That is the truth, as the scientific evidence overwhelmingly demonstrates.

tl;dr: vaccines ARE NOT effective.

*** PART 2 ***

The risks posed by vaccination:

Infants are born with extremely undeveloped immune systems. Infants are not able to mount more than the feeblest response to glycoprotien-based antigens until 6-9 months after birth, and are not able to mount a strong defense to polysaccharide-based antigens until 24 months. Effectively, until a child is at least 12 months of age, their immune system is ineffective and they depend on antibodies that crossed the placenta during pregnancy or those found in breast milk in order to mount an effective defense to any form of infection. During this period of development, the immune system is particularly vulnerable to upregulation of the Th2 system and downregulation of the Th1 system, as this is the time period when T cells are initially programmed in the thymus. Interference with normal development, or the hijacking of the "infection" process can cause T cells to become improperly programmed, making infants and toddlers particularly vulnerable to developing allergies or autoimmune conditions.

That vaccines cause autoimmune conditions is without question. Read any vaccine insert and they list numerous autoimmune conditions caused by that particular vaccine during clinical trials. There is not one vaccine on the market that does not share this "feature". There are entire medical textbooks on this issue, such as Vaccines and Autoimmunity, published by Wiley/Blackwell (amazon.com/Vaccines-Autoimmunity-Yehuda-Shoenfeld/dp/1118663438). This is called Autoimmune Syndrome Induced by Adjuvants, or ASIA.

Adjuvants are agents used in non-cellular vaccines to selectively piss off the immune system in the region of the vaccine injection, and are often bonded to the antigen that the immune system is supposed to target. This causes two major effects: first, it increases inflammation at the site, drawing more leukocytes (white blood cells) to the area of injection and increasing the odds of an immune response, and secondly, it kills cells in the injection area releasing cytokines that further attract leukocytes.

Where things go wrong is how the "infection" doesn't become acute, preventing a Th1 response, and that macrophages drawn to the cellular bloodbath accidentally present non-targeted antigens to T cells, causing both allergies to any vaccine additive or food antigen that happened to slip into the bloodstream and autoimmune responses.

Another cause of vaccine damage is response to vaccine ingredients themselves. DNA fragments in the vaccines can cause cells to mutate, potentially becoming cancerous. Preservative agents in vaccines (being preservative agents because they are toxic) can directly damage the patient's cells, and often selectively target the nervous system. Adjuvants such as aluminum can migrate in the body, damaging both vital organs and the nervous system. This topic alone is so well-documented in the medical and scientific literature that it is beyond the scope of this course: for more information, do a Google Scholar search of anything aluminum-related by Dr. Christopher Shaw.

Without a doubt, vaccines are not safe. Vaccines can and do cause autoimmune diseases, allergies, and death.

Children who were under-vaccinated due to parental choice had significantly lower rates of emergency department visits. (ncbi.nlm.nih.gov/pubmed/23338829)

Infants who received several vaccines concurrently were the most likely to be hospitalized or die. This trend was more pronounced the younger the age of the child. (ncbi.nlm.nih.gov/pubmed/22531966)

“The current findings indicate that there are clusters of cases of type 1 diabetes mellitus occurring 2-4 years post-immunization with the pertussis, MMR, and BCG (tuberculosis) vaccines.” (ncbi.nlm.nih.gov/pubmed/12793601)

This study analyzed the vaccination schedules of 34 developed nations and found that nations requiring the most vaccines tend to have the worst infant mortality rates. (ncbi.nlm.nih.gov/pmc/articles/PMC3170075/)

Immune throbocytopenic purpura is an autoimmune disease that causes internal bleeding and can be life threatening. ITP is 5 times more likely to occur after MMR vaccination (IRR = 5.48). Children were twice as likely to have convulsions 6 to 11 days after MMR (RI = 2.07) and 7 times more likely to develop ITP 6 weeks after MMR (RI = 6.91) compared to the period prior to MMR. (ncbi.nlm.nih.gov/pubmed/24763539)

Pertussis-vaccinated children were 14 times more likely than unvaccinated children to be diagnosed with asthma (HR = 14) and 9 times more likely to be diagnosed with eczema (HR = 9.4). (ncbi.nlm.nih.gov/pmc/articles/PMC1448377/)

“Aluminum has been demonstrated to impact the central nervous system at every level, including by changing gene expression. These outcomes should raise concerns about the increasing use of aluminum salts as vaccine adjuvants.” Aluminum-adjuvant vaccines can cause macrophagic myofasciitis. Clinical symptoms include myalgia, arthralgia, chronic fatigue, autoimmunity, and cognitive dysfunction. (ncbi.nlm.nih.gov/pubmed/25428645)

Aluminum-injected mice showed significant deficits in memory and motor functions. They also had pathological abnormalities characteristic of neurological diseases such as Alzheimer’s and dementia. (ncbi.nlm.nih.gov/pubmed/19740540)

*** Part 3 ***

Muh herd immunity:

Anybody that cites herd immunity as a reason for vaccination is an imbicile. Full stop.

Read academic.oup.com/aje/article-abstract/11/3/576/63159?redirectedFrom=fulltext.

Consider that back when the concept of herd immunity was born, it referred to naturally acquired immunity: lifetime immunity conferred by contracting and overcoming a disease. This is a “real thing”, but the question is whether or not it could be achieved today through artificial immunity. When you read the above, an uncritical interpretation would think that only 55% of the population being protected would confer this benefit, but what this fails to consider is that of the population over the age of 15, nearly everyone was immune by virtue of past infection. When examined from that perspective, if 25% of the population was under the age of 15, the threshold for herd immunity among the entire population was actually 88-89% immunity. Due to how artificial immunity wanes over time, this can never be achievable through childhood vaccination efforts.

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Today, by the time an individual is old enough to drink, there is a good likelihood that their vaccine-derived immunity to measles (for example) has waned. By the time they reach 30, very few people will have any protection at all. Assuming the government mandated 100% vaccination of our children, since adults aren’t given any form of booster (and indeed, each additional booster of a particular vaccine confers less immune response than prior doses), we could never reach more than a 30-40% immunity rate … and that’s assuming that vaccines are 100% effective! Even the CDC openly admits this isn’t the case, yet the immense and obvious gulf between what they tout as “herd immunity” and what was previously demonstrated is ignored in favor of propaganda in support of mandatory vaccination. As the baby boomer generation dies off, the last vestiges of our population’s natural immunity will die with it: this problem will only grow more pronounced with time.

*** Part 4 ***

Diseases are more dangerous than vaccination!:

Go back to part 1 and reread it. Then do it again. For statistical analyses of the risks of diseases (in the US) when compared to the risks of vaccination, using numbers provided by the NIH, CDC, WHO, FDA, and VAERS, go to raisinghealthychildren.net and browse each individual disease in the vaccination section. There is not one case in which any single disease is more risky than the vaccine preventing it, with the exception of the hepatitis B vaccine in babies born to HepB+ mothers. Not one. While this contradicts the propagandistic fear-mongering of the media and CDC, math doesn't lie.

*** Part 5 ***

Why this belongs on Jow Forums, and why this should matter to you:

Currently, there are pushes both by private and governmental groups to censor any information or research that calls vaccination into question. Vaccination skeptics are being silenced and scapegoated for the general decrease in public health by individuals such as Bill Gates and the WHO which actively promote negative population growth, while governments from the federal to the local level are actively seeking increasingly draconian vaccination mandates. In CA, a bill has been introduced to make it extremely difficult and onerous for physicians to grant medical exemptions to vaccination. In NY, unvaccinated minors are barred from public on penalty of arrest and fines. For those that understand the problematic nature of vaccines, medical choice is rapidly being replaced by government mandate by politicians who are actively paid by the very pharmaceutical companies that manufacture vaccines ... companies that are granted immunity from litigation related to their products ... products that have never been subjected to a double-blind placebo study like any other drug would. Even if you still believe that vaccination is the right choice for you, you should fight like hell against this replacement of medical autonomy by government mandate.

Vaccines are not safe. Vaccines are not effective. Vaccines increase your risks from infection and cancer. Vaccines kill otherwise healthy children daily.

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"Among 3–5-month-old children, having received DTP (± OPV) was associated with a mortality hazard ratio (HR) of 5.00 (95% CI 1.53–16.3) compared with not-yet-DTP-vaccinated children. Differences in background factors did not explain the effect. The negative effect was particularly strong for children who had received DTP-only and no OPV (HR = 10.0 (2.61–38.6)). All-cause infant mortality after 3 months of age increased after the introduction of these vaccines (HR = 2.12 (1.07–4.19))." (ncbi.nlm.nih.gov/pmc/articles/PMC5360569/)

There are hundreds of new vaccines in the pipeline, and none are being subjected to double-blind placebo studies for safety. The CDC's stated policy is that any approved vaccine is to be added to the recommended schedule. Most states follow this schedule for vaccination mandates. While the current risks posed by vaccination are already clear, this problem will only get worse, and as of last month the CDC published a vaccination schedule for adults. Unless the thought of being forced to endure multiple injections of unsafe and harmful drugs on pain of being forced into house arrest makes your panties moist, every one of you needs to work to prevent the removal of vaccine exemptions.

“Our results show that: (i) children from countries with the highest ASD prevalence appear to have the highest exposure to Al from vaccines; (ii) the increase in exposure to Al adjuvants significantly correlates with the increase in ASD prevalence in the United States observed over the last two decades (Pearson r = 0.92, p < 0.0001); and (iii) a significant correlation exists between the amounts of Al administered to preschool children and the current prevalence of ASD in seven Western countries, particularly at 3–4 months of age (Pearson r = 0.89–0.94, p = 0.0018–0.0248). The application of the Hill’s criteria to these data indicates that the correlation between Al in vaccines and ASD may be causal.” (sciencedirect.com/science/article/pii/S0162013411002212)

“Ten percent of pediatricians and 21% of pediatric specialists claim they would not follow [CDC] recommendations for future progeny. Despite their education, physicians in this study expressed concern over the safety of vaccines.” (scirp.org/journal/PaperInformation.aspx?PaperID=22932)

Children who received 3 or more doses of hepatitis B vaccines had a significantly increased risk of leukemia (OR = 2.6). Infants who receved hepatitis B vaccines were approximately 5 times more likely to develop leukemia. (ncbi.nlm.nih.gov/pubmed/15951359)

Measles, rubella, and chickenpox infections during childhood protect against many different types of cancer later in life. Adults were significantly protected against non-breast cancers (genital, prostate, gastrointestinal, skin, lung, ear/nose/throat, and others) if they contracted measles (OR = 0.45), rubella (OR = 0.38) or chickenpox (OR = 0.62) earlier in life. (ncbi.nlm.nih.gov/pubmed/9824838)

Women diagnosed with systemic lupus erythematosus were 5 times more likely than controls to have received the HPV vaccine (OR = 5.3). Women diagnosed with alopecia (OR = 8.3), gastroenteritis (OR = 4.6), vasculitis (OR 4.0), and central nervous system conditions (OR = 1.8) were also significantly more likely than controls to have received the HPV vaccine. (ncbi.nlm.nih.gov/pubmed/25535199)

"Let your kids die from prevventable illness now so they don't die from cancer later."

- you right now

Which one would that be? The only diseases that are anything more than extremely rarely deadly are pertussis and meningitis. The meningitis vaccine lasts for two years and doesn't confer immunity, it only possibly reduce symptoms. The pertussis vaccine is almost entirely ineffective in infants (their immune systems can't respond), can't prevent infection, and at best lessens the symptoms once infected. Oh, and you can get reinfected multiple times if vaccinated.

What then? Measles? There has been one confirmed death in the US from measles in the last 25+ years. Chickenpox? How many decades has it been since there was a case of polio (which was caused by the vaccine)? Which preventable disease are you referring to?

In contrast, multiple children die from vaccination every day. Shill.

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"The aluminium content of brain tissue in autism was consistently high. The mean (standard deviation) aluminium content across all 5 individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) μg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively. These are some of the highest values for aluminium in human brain tissue yet recorded and one has to question why, for example, the aluminium content of the occipital lobe of a 15 year old boy would be 8.74 (11.59) μg/g dry wt.?" (sciencedirect.com/science/article/pii/S0946672X17308763)

This measles outbreak occurred in an adult population with high 2-dose measles vaccination coverage. The primary patient had documentation of receipt of 3 doses of measles-containing vaccine, one each at ages 1, 2, and 6 years, per the vaccination schedule in Ukraine. Although it is possible that the vaccination record contained an error, the high IgG avidity suggests secondary vaccine failure. All patients except one had high measles IgG avidity, which is an indicator of previous vaccination or previous infection. Because all the serum specimens (except that from the primary patient) were collected 2–3 days after the onset of symptoms, the high avidity IgG was assumed to be a result of patients’ previous vaccination. (cdc.gov/mmwr/volumes/67/wr/mm6742a4.htm)

You are the only one stupid enough to believe this shit. Darwin's theory at it's finest

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A wild shill appeared!

Sure, it's just me, every A&P textbook, every microbiology textbook, every immunology textbook, and tens of thousands of peer-reviewed scientific journal articles. I even linked some for your lazy ass.

"Thus, we conclude that aP vaccination interferes with the optimal clearance of B. parapertussis and enhances the performance of this pathogen." (ncbi.nlm.nih.gov/pmc/articles/PMC2880100/)

Barney the dinosaur here. Very interesting stuff. Wonder why the screeching from the media lately about vaccines?

"Severe (grade III) tetanus occurred in three immunized patients who had high serum levels of anti-tetanus antibody. The disease was fatal in one patient. One patient had been hyperimmunized to produce commercial tetanus immune globulin. Two patients had received immunizations 1 year before presentation." (ncbi.nlm.nih.gov/pubmed/1565228)

Insane Th2 immunity to tetanus with clinically documented titers? Well fuck you buddy, you're going to die anyway. That's how "effective" vaccination can be.

For most media outlets, pharmaceutical advertising makes 40-60% of their total revenue. If a news agency allowed reporting on vaccine deaths or injuries, or insinuated that there were risks, or went so far as to not use the phrase "vaccines are safe and effective" in any report that mentioned vaccines in any way, they would be instantly bankrupted by lack of revenue.

seems interesting bump

"The 1989 measles outbreak in the province of Quebec has been largely attributed to an incomplete vaccination coverage. In the Quebec City area (pop. 600,000) 1,363 confirmed cases of measles did occur. A case-control study conducted to evaluate risk factors for measles allowed us to estimate vaccination coverage. It was measured in classes where cases did occur during the outbreak. This population included 8,931 students aged 5 to 19 years old. The 563 cases and a random sample of two controls per case selected in the case's class were kept for analysis. The vaccination coverage among cases was at least 84.5%. Vaccination coverage for the total population was 99.0%. Incomplete vaccination coverage is not a valid explanation for the Quebec City measles outbreak." (ncbi.nlm.nih.gov/pubmed/1884314)

"That’s why a fully vaccinated 22-year-old theater employee in New York City who developed the measles in 2011 was released without hospitalization or quarantine. But like Typhoid Mary, this patient turned out to be unwittingly contagious. Ultimately, she transmitted the measles to four other people, according to a recent report in Clinical Infectious Diseases that tracked symptoms in the 88 people with whom “Measles Mary” interacted while she was sick. Surprisingly, two of the secondary patients had been fully vaccinated. And although the other two had no record of receiving the vaccine, they both showed signs of previous measles exposure that should have conferred immunity.

"A closer look at the blood samples taken during her treatment revealed how the immune defenses of Measles Mary broke down. As a first line of defense against the measles and other microbes, humans rely on a natural buttress of IgM antibodies. Like a wooden shield, they offer some protection from microbial assaults but aren’t impenetrable. The vaccine (or a case of the measles) prompts the body to supplement this primary buffer with a stronger armor of IgG antibodies, some of which are able to neutralize the measles virus so it can’t invade cells or spread to other patients. This secondary immune response was presumed to last for decades." (sciencemag.org/news/2014/04/measles-outbreak-traced-fully-vaccinated-patient-first-time)

That's what happens when you make assumptions, idiots. ~40% of measles cases in the US are currently caused by vaccine-strain measles, vaccination doesn't confer absolute immunity even if it caused an immune response, and the only lifetime vaccine is currently believed to be rubella.

"Our previous ecological studies of autism spectrum disorder (ASD) has demonstrated a correlation between increasing ASD rates and aluminium (Al) adjuvants in common use in paediatric vaccines in several Western countries. The correlation between ASD rate and Al adjuvant amounts appears to be dose-dependent and satisfies 8 of 9 Hill criteria for causality. We have now sought to provide an animal model to explore potential behavioural phenotypes and central nervous system (CNS) alterations using s.c. injections of Al hydroxide in early postnatal CD-1 mice of both sexes. Injections of a "high" and "low" Al adjuvant levels were designed to correlate to either the U.S. or Scandinavian paediatric vaccine schedules vs. control saline-injected mice. Both male and female mice in the "high Al" group showed significant weight gains following treatment up to sacrifice at 6 months of age. Male mice in the "high Al" group showed significant changes in light-dark box tests and in various measures of behaviour in an open field. Female mice showed significant changes in the light-dark box at both doses, but no significant changes in open field behaviours. These current data implicate Al injected in early postnatal life in some CNS alterations that may be relevant for a better understanding of the aetiology of ASD." (ncbi.nlm.nih.gov/pubmed/23932735)