copped some St. Johns Wort because I heard it helps depression and lethargy. When should i take it and what doseage? Anyone have any experiences with it or Ashwaghanda?
Is it worth taking? I also have mild bipolar, as in rapidly shifting moods. Will this fuck me up or my gains?
It's a COMT inhibitor, which is an enzyme that degrades catchomines like epinepherine and dopamine. More catchomines = more energy and motivation, which is good on a cut and I guess if you're a mopey fagget
Jackson Gutierrez
I am a mopey fagget though. struggle to get up in the mornings. Do i need to load up on this? Or cycle?
Nathan Cooper
There's no tolerance, take 3-4 servings a day if you want, just keep in mind it might interfere with sleep if you take it late in the day. Also it's a mild COMT inhibitor so don't expect miracles. I don't know what brand that is pictured by get a patented formula instead of random bullshit.
Also, wear sunglasses if it's bright out and you're taking a ton.
Wyatt Bell
Why would you want to inhibit dopamine? Isn't that the happy drug?
Hunter Evans
Are you illiterate? I'll say it again in shorter sentences: COMT is an enzyme. COMT is an enzyme that degrades, reduces, inactivates catecholamines. Catecholamines are a category of endogenously-produced compounds like dopamine and adrenalin. More COMT means less catecholamines. St John's Wort is a plant that contains a compound called hyperforin. Hyperformin when ingested reduces the expression and action of COMT. Does this make sense yet?
Jace Moore
Not the OP, but thank you for the explanation in bite size sentences.
L-Tryptophan would be better if you`re white. The hypericin in St. Johns Wort makes you more sensible against sunlight. Also the effect is also based on reducing Beta- Adrenoreceptors.
Levi Gutierrez
It made me more depressed when I took it lol
Wyatt Hall
can cause cataracts
Carson Sanders
I take one dose of 3750mg of ashwagandha daily. supposedly takes a week or two to really start building up the effects and I'm pretty sure my boner game is increased a gorillionfold
Jaxson White
Don't. St. John's Wort has a lot of side effects photosensitive (literally permanent bruising from the sun and can ruin your eyesight from direct sunlight) is one of the worsts side effects.
Take Sam-E, that shit cured my depression. I tried it on a whim and it made me realize my depression was way worse than I thought. Completely changed my life. I've been on it for 3 months or so but I foresee taking it for maintenance for the long term.
You'll notice a difference within a week, I take 1600mg a day.
0 Side effects and it's a natural occurring element in the body with high bio-availability (no known toxicity.)
I've tried a lot of different brands but Nature Made is the best.
Good luck user.
Jackson Price
I've been wanting to try creatin but I'm not sure about dosing I've been training for about 2 years and weigh ~150, anybody got any advice? Maybe also about other supplements I should be taking (besides whey protein)
Jack Kelly
>jargon jargon jargon jargon jargon
DOES THIS MAKE SENSE YET IDIOT
Evan Nguyen
Thoughts on turmeric supplements? Meme or what?
Luis Nelson
Because one you get a dopamine hit you lose motivation. It's your body's signal "well we already did the thing that feels good, might as well do nothing now that it's over"