Biomedical gerontologist Aubrey de Grey (PhD...

> wages
> employment

We're obviously not going be using that model for more than a few decades more. Have you not been paying attention to AI at all?

Are you trolling?

A pedophile is not a child molester for starters and he is not a retard. If what people 'got' what they deserved you're falling for a belief system that promotes no self improvement or hard work and effort. In the end believing everyone will receive a just and divine reward or punishment is a weaklings belief, you are too afraid to change yourself and so you wait for karma to reward or punish or reward people.

>A pedophile is not a child molester
what does that have to do with anything?

AI has been "decades away" for 40 years now. Shit's hard.

>Hurr AI is going to replace all the jerbs

Stop watching the discovery channel or whatever the fuck is it that has convinced you that AI is mere decades away from replacing all types of employment.

and roasties like you deserve to be alone
oh wait you will

I feel like people would take him more seriously if he shaved that ridiculous hobo beard. Unfortunately, humans are superficial and outward appearance is incredibly important in making a good impression.

Things have changed in the last 10 years. Artificial neural networks have made an awful lot of progress, and it now seems quite clear that we're reaching an inflection point.

In 10 years, I think it'll be obvious to everyone that AGI is quite close. We are likely to get there by 2035.

A pedophile has an attraction to children, they can choose to act on their desire and become a child molester or they can choose to control their desires. While all child molesters are pedophiles not all pedophiles are child molesters. A person that sexually abuses children deserves punishment, a person that wants to do something but chooses not to act on that desire does not deserve punishment.

You are looking to police people for things they have not done, EVERYONE has thought about hurting someone else, we all get angry and we think and maybe even say we want to murder, maim or just punch a person. Does this mean we should all be sentenced to death/imprisonment for our thoughts?

People make decisions to act or not to act on a desire every day. Many choose not to act on base instincts because we know they are morally, legally or socially unacceptable. Punish people for their actions and not their thoughts, a pedophile that has never molested a child is as admirable as a suicidal person that never kills themselves or a person with thoughts of violence and rape that consciously chooses to ignore these impulses.

>1980
>Just ten years guys
>1990
>10 more years
>2000
>Mere decades away!
>2010
>Woah look out it's coming!
>2018
>Just wait until 2035

On a side note, Aubrey just contributed to a 60 year old math problem. Guy's a genius.
quantamagazine.org/decades-old-graph-problem-yields-to-amateur-mathematician-20180417/

this

triggered pedo detected lol

This link is actually in the OP

Well, you'll just have to wait and see. If I'm wrong, I'm wrong, and I'll pay the price.

I hope you're not planning your life around some forlorn hope for Universal Basic Income provided on AI labor. For all businesses and places of employment to switch to such methods the AI would need to be unrealistically cost effective and efficient. Machines also break down constantly, they aren't a one off purchase that makes a person endless money, they require maintenance, cleaning and power just like a human except humans clean and feed themselves from their own pocket. I swear people like (You) are like those that think being a landlord is just endless money. Because obviously owning a second house or a robot is just like owning a money printer.

>pssh yeah paying a human to clean and fix my robot it is still cheaper
Not if that human requires a 4 year degree in mopping up robot fluid and reconnecting loose wires which will happen I assure you.

You might find large businesses using it but small businesses will be just as cheap and efficient and have better customer service than an assembly line. Even assuming your AI is cheaper, more effective and beats a human for customer service you know what politicians will do to ensure re-election? They'll tax the shit out of majority AI businesses to the point that they're on par with AI free businesses just to please voters.
TL;DR: Get a job hippy because it's not happening any time soon.

The super rich will be immortal not you.

what a great fitness thread amirite guys? fucking faggots.

>Biomedical gerontologist Aubrey de Grey (PhD, University of Cambridge) believes that we have at least a 50% chance of achieving 'longevity escape velocity' (adding more than 1 year to our remaining lifespan each year) within the next 20 years. He has invested almost his entire net worth (less the value of his personal effects and primary residence) into a foundation working towards this goal, the SENS Research Foundation, based in Mountain View, California. (www.sens.org).
Lol. Didn't like the answers last time, huh?

This has always been a massive meme. Drug companies don't spend hundreds of millions researching and developing a product and then sell that product to 1% of the population. At first sure they'll lie and say "production costs justify this price" to milk the super rich but once that money has been spent suddenly "woah we can produce a lot more now ;)"

Pharmacy money is made from the 100,000 plebs paying $100 and not from the one rich guy paying $100,000. What is much more likely is them creating a product that requires constant use to remain effective, a million people paying $100 a month for a "youth pill" is endlessly more profitable than any other alternative. The best part for the company that makes the first pill? Endless demand, population growth going out of control only means more profit for them.

> I hope you're not planning your life around some forlorn hope for UBI

No, I work in software. Before starting a company 3 years ago I had trained as a lawyer in the UK, but had to make the change after I recognised an opportunity that I wouldn't be able to pursue while also in law full time.

The board is 'health and fitness' and ageing is definitely related to both health and fitness.

The last thread got over 300 replies, hitting the bump limit and got archived. I was very pleased with the variety of perspectives I got to read about, even though I disagreed with many of them, and I want to read more opinions even though I know I will surely disagree with many them.

I'm not looking for 'confirmation', but rather trying to discover what people expect in relation to this theory and why they expect it.

My family has a history of pancreatic cancer and neurosis/autism/schizophrenia, so i'm one of the lucky ones. The benefits outweigh the costs since my family is full of /sci/entifically /lit/fit/erate people.

Might be getting some symptoms already, i'm a paranoid fuck and can't make friends but i'm reading /lit/erature to cover that base, and i am prone to falling for conspiracy theories but i try to remain agnostic to all of them so i don't lose my shit, i'm convinced the nsa is watching me thoguh, got a solid grip on reality (for the most part) because my deductive reasoning is solid. Have violent antisocial tendencies but keep that shit hidden unless it works to my advantage. Not a good manipulator but that's because i'm probably retarded, could probably do it adequately too... I once almost strangled my cat to death because of anger and a voice, the cat survived because i pitied it at the last second but i felt no remorse for doing it so i'm probably already a lost cause, don't want to break the law yet, hope to take over my local gov and live my last years as a dictator.

Why am i telling you all this? dunno, just feel like telling someone.

I'm with ya buddy, i get ya. Life is hard but you just fight through it until something good happens, you are no one's bitch but your own.

Mind telling me the secret so i can try it out OP?

There is no secret. All their research is published and peer-reviewed. See www.sens.org for details.

Why?

i really hope aubrey has a chance to make it, guy sacrificed his life to this. his death would be his ultimate failure

He's quite pro-active and monitors his health carefully. His lab results suggest that he's in the health of a typical ~40-year-old, and he's actually 54.

He doesn't do anything special at the moment, so he's just lucky so far. He has specifically said that he doesn't do anything special (not even dietary) because the evidence suggests that the effect sizes are very small for most of the normal things people do to try to live as long as they can.

We're all going to make it.

They said he could be anything, so he became immortal...

bluepilled

He looks a lot younger than 54. What's his secret?

He seems like a brainlet but he has a worthy goal.
I too am working on phd on antiaging

What is your theory?

constant autophagy through activation of sirtuins through precursors
Check out David Sinclair, guy in OP is a wannabe David Sinclair

Oh, I'm familiar with him. Aubrey seems to admire Sinclair's work, but I'm not sure if the two have discussed each other's strategies in detail.

twitter.com/aubreydegrey/status/422120858694324224?lang=en

Has autophagy been studied in humans?

watched a documentary on this guy and his buddy. they're basically quacks that have an immortality obsession. kinda depressing to watch

Yea, it's the benefit of caloric restriction
aka its the reason why people due fasts and intermittent fasting

If Sinclair's work can be perfected, we can have a drug that just activates autophagy without having to starve for prolonged periods of time, and at a greater rate.
Lot's of money to be made basically

plus if we can activate autophagy before our telomeres degrade completely, longevity is guaranteed and can buy us more time to look into other factors that cause aging

end game is to produce immortal cell lines that self repair and replicate in vivo.
Autophagy just deals with misfolded proteins, etc, like putting a bandaid on but not extending life.
People are already working on inserting genes from stem cells into the DNA of defective cells, but we need to locate all of the causes of aging, repair those cells, and have them replicate in the body.
Good luck /fitsci/ we all gonna make it

is not eating a problem when theres no hunger though?

youtu.be/LylJ0OOcONg
this guys theory is that telomere length varies between cells and is basically irrelevant. he mentions it somewhere in this presentation
his approach is delaying aging by reducing mTOR, which will eventually cause cancer growth, and keeping autophagy up to get rid of old mitochondria that slow down proper metabolism

not eating for the sole purpose of autophagy is not favorable imo. I want to be able to eat what I want, and build muscle mass while enjoying the benefits, etc. and autophagy from fasting alone won't make you live to 200

I think it's commonly accepted that DNA degradation from losing telomeres is a big factor in aging, he hasn't disproved it.
but yea, mTOR is interesting, sirtuins seem to have a negative correlation with them, and autophagy in general.

Sirtuins, mTOR inhibition, and IIS are all probably linked anyway.
jbc.org/content/early/2017/03/06/jbc.R116.771915.full.pdf

There's already mTOR inhibition drugs on the market
ncbi.nlm.nih.gov/pmc/articles/PMC3972801/

webmd.com/drugs/2/drug-17701-5301/sirolimus-oral/sirolimus-oral/details

Sirolimus/resveratrol/NMN stack for age gains

I haven't seen this guy before, thanks for link user.
Nice to see some support for keto

But have studies been done in humans that show at which point autophagy begins? Is there even a way to measure it in humans?

There probably is. Its an area of great interest for researchers
ncbi.nlm.nih.gov/pmc/articles/PMC3879707/#bib2
Check out the references at the bottom of this article to start

>implying any of us will be able to afford this shit
Also a widely available longevity solution will absolutely rek society. You think there's overpopulation now?

>literally have a good diet, exercise, sleep well
Gain a decade or two of healthy life

Also
>implying non first worlders will have longevity solutions available to them when they don't even have clean water and shit

Yeah, but think about it. Even if you are rich now, your kids and their kids etc. living to 500 will seriously dilute that wealth. How long until we are scraping for clean water?

yeah "his" pov is retarded.

what if when they invented cars everyone said "human beings don't deserve chariots that too closely resemble the old gods"

that's what you sound like now

>implying ill get to reproduce even if i live for 500 more years

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>everyone deserves what they get
>the_weak_should_fear_the_strong.jpg

>You think there's overpopulation now
No.
We simply can't afford to keep the current status quo going with the amount of people we have.

I mean, that IS going to happen. It's just a question of whether you live long enough to see it.

for example in the next 5 or so years all trucking/bussing/taxi jobs will be overtaken by autonomous cars, and factories will continue to become more and more robotic.

if they're already making sex robots, it's only a matter of time before similar models are the ones handling people in department stores at malls

Isn't that the same thing?

correction, the super rich will become immortal FIRST*

when it first comes out it will cost 5 million dollars, and by the time it becomes affordable to the normal person the rich elites will already be paying for the next 10 million dollar therapy that allows them to live another 200 years than the one you're currently paying for.

they'll always be a step ahead of everyone else

>Doesn't realize we're stuck in hell and death is the only way to progress to higher planes of existence

No thanks, I'm not going to be some cuck scared of death.

Nope.

Hahaha

philosophical question:
If immortality was to be discovered
Do you take your chance that there is an after life and die?
Or do you choose to live in the life you have now forever?

Reverse Pascal's Wager

HUMANITY IS GOING INTERSTELLAR.

>tfw you realize this justification is how you made yourself accept being okay with dying someday

and now the glimmer of hope that you might not die when you thought you would completely clashes with the thing that made death comfortable for you in the first place

We can increase the carrying capacity of the Earth, just as we have before.

And we are going to other planets. First Mars, but well beyond that.

lol, no. A few years at most. Obviously smoking and eating like a pig removes years off your life but, otherwise, there's nothing that you can do to live longer.

Indeed. Even if we completely eliminated all forms of cancer, it would only add something like 3 years to the average lifespan, because so many systems of the body malfunction at about the same time, so the benefit from solving only one age-related problem is quite small. We have to develop strategies that address all age-related pathologies, or we're always going to come up against something once we get into our 80s and 90s.

fasting might add a few years to your life

unlikely if you have a good diet as your base.

Bad diets can easily take years off your life, but a 'great' one can't reliably add much.

>Biomedical gerontologist Aubrey de Grey (PhD, University of Cambridge) believes that we have at least a 50% chance of achieving 'longevity escape velocity' (adding more than 1 year to our remaining lifespan each year) within the next 20 years. He has invested almost his entire net worth (less the value of his personal effects and primary residence) into a foundation working towards this goal, the SENS Research Foundation, based in Mountain View, California. (www.sens.org).
>
>De Grey estimates that the SENS Research Foundation requires approximately $40m in annual funding to maximise the pace of the research - the limiting factor at that point being the inherent difficulty of the science.
>
>The Foundation currently has approximately $5m in annual funding, and De Grey estimates that the speed of progress is currently only about a third of what it would be at $40m/year.
>
>Do you believe in this project? Can it be achieved at all, on any timescale? And is it likely, in your view, that we will reach 'longevity escape velocity' in a ~20 year timeframe?
>
>A brief introduction to his ideas and work: youtube.com/watch?v=x2o8LKdFtmY
>
>Read his PhD manuscript here: sens.org/files/pdf/MiFRA-06.pdf
>
>See here for his academic credentials: sens.org/sites/srf.org/files/AdG-CV.doc
>
>And see here for details of the members of the Scientific Advisory Board of the SENS Research Foundation: sens.org/about/leadership/research-advisory-board
>
>Here’s a recent video with BBC News: bbc.co.uk/news/av/technology-43402894/aubrey-de-grey-treating-ageing-as-a-curable-disease
>
>Aubrey solves decades-old ‘unsolvable’ math problems for fun in his spare time: sciencemag.org/news/2018/04/amateur-mathematician-cracks-decades-old-math-problem, quantamagazine.org/decades-old-graph-problem-yields-to-amateur-mathematician-20180417/
imagine if ZZ Top had let him join their band when he asked

Attached: images.jpg (230x170, 9K)

ZZ Top wishes that Aubrey would join them. He's simply too busy saving humanity.

don't just give up user

if you can make me like pic related minus the cancer and crispy chicken tender skin, sign me up

Attached: images.jpg (1300x701, 70K)

we'll do our best

scam, it's mathematically impossible to stop ageing (for humans). only hydras and telomerase able animals live forever

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thanks. also don't kidnap me or anything like that plsthx

Actually a lot of child molesters aren't even pedophiles, they just do it to have power over someone or inflict pain. They molest a child because it's easier than overpowering an adult

yes it would be prety cool to live a few hundred years , you could see a small forest grow to a massive one , see an acorn turn into a massive Oak . but i believe that most people would not see it that way and would end themselves after say 200 at most . plus people would still die , from accidents and suicides drug overdoses and the like and the population would need to be sterilised too

shut up Griffith, you had your chance but you chose to give up twink mode and your gains to become super batman

do you need to be rich to live 180+ years?

If we don't get rid of the Jews in the next 50 years, we won't in the next 5000 either. The Jewish problem is a problem now, not in 500 years.

I would take a pill knowing I would live forever, with the caveat that I can eat the end of a shotgun at any point I choose. The question is could a person handle that responsibility wisely, and how would choosing when to die affect what a person does and how they think.

I don’t know if the human brain is built to live 200 years and not succumb to illness of some sort, be it a physical change or merely a psychological one.

Being rich is having powerful connections. Not money.

that's just sad

maybe we'd be a lot nicer if we lived extremely long lives and made fewer new people

If we don't get rid of Jow Forums in the next 50 posts, we won't in the next 5000 either. The Jow Forums problem is a problem now, not in 500 posts.

Nationalism has little to do with Jow Forums. People all over the world are waking up to the Jewish question. Trump and brexit are just the beginning.

how so?

Because everything the Jews have done for the past 70 years was done in order to progress towards a society in which they can never again be challenged.

They don't intend to just keep their current power. They want much, much more. And this is primarily done by trying to infiltrate and weaken those that possess the biggest potential threats to them.

Every year, they grow stronger, while we grow weaker. Soon we reach the point of no return.

Same goes for living forever.
We'll achieve them both within a few decades of each other imo.

>while we grow weaker

speak for yourself *flexes*