Researchers at Japan’s RIKEN Center for Developmental Biology (annual budget: $760 million), where Dr. Takashi Tsuji runs one of the most advanced stem cell labs in the world, have developed a method to autonomously regenerate fully functional hair follicles and teeth from autologous tissue samples, and the method has been demonstrated in an animal model.
A company (Organ Technologies) has been formed to commercialise the technology in partnership with Japanese precision manufacturing giant Kyocera Corporation.
In the joint venture Kyocera will be developing the cell processing devices and RIKEN and Organ Technologies will be responsible for the stem cell culturing and manipulation, the production process, and implementation of the preclinical trials.
The treatment involves extracting a small number of hair follicles from a person’s donor scalp area and then isolating two specific types of cells from the follicle – papilla cells and epidermal cells from the bulge region.
These cells are then cultured, expanded, and combined to create a hair follicle “germ” or “follicular primordium.” Once the hair follicle germs are ready they are transported to a facility where they can be implanted back into a person’s scalp to grow hair permanently.
Because this method involves the creation of new dht-resistant hair follicles, any desired level of coverage and density can be achieved. Only a few square centimetres of donor skin would be required to generate a full NW0 level of coverage at any desired level of hairs per square centimetre.
Clinical trials begin this year in Japan, and pending approval by regulatory authorities the treatment will be commercially available in Japan in the year 2020.
Researchers have developed the means to engineer mass regeneration of hair, which they said raises the prospect of a cure for baldness being commercially available as early as 2020.
The announcement promises to be a godsend for baldies everywhere, including the 18 million individuals in Japan afflicted by hair loss.
Scientists at the Riken research institute who teamed up with Organ Technologies Inc., a Tokyo-based medical business venture, said they hope to begin clinical trials in 2019 on men suffering from hair loss if no problems occur.
They announced June 4 the development of a way to mass produce hair created by cultivating scalp cells into hair follicles.
The research team is headed by Dr. Takashi Tsuji of Riken.
"The latest results indicate that we have gone beyond the research stage," Tsuji said. "Regenerative medicine for hair is an area of high social interest. We will seek to industrialize a technology born in Japan."
The research team has been involved in various technologies to deal with hair loss. In 2012, the team cultivated human scalp cells and produced hair follicle cells. When the hair follicle cells were transplanted to the backs of hairless mice, hair started to sprout.
The latest development involves creating equipment that allows for more efficient mass production of such hair follicle cells, while ensuring that the integrity of three different types of stem cells taken from human scalp cells and used in the cultivation process is maintained.
The technology allows for the hair to regenerate itself after being transplanted, meaning the hair growth cycle can be sustained.
Hair follicles that could produce 10,000 strands of hair were created after 20 days or so from 1 square centimeter of scalp.
From July, the research team plans to transplant the hair follicle cells to the backs of mice in order to confirm the safety of the technology.
Researchers are keen to determine if any allergic reaction occurs or if tumors develop. If no problems emerge, clinical trials could get under way in 2019.
This raises the prospect of a commercial cure becoming available in 2020.
We need to run this through a few decades of trials first before we can authorize such a dangerous procedure.
Camden Phillips
This was on an episode of Seinfeld in the fucking 90s. George called China because they developed a baldness cure but the chinks couldn't understand him. I'm sure in 1998 people thought it was right around the corner too. It's been 20 fucking years. People have died waiting. I'll believe it when I see it. Until then team shaved head
The human trial begins in March 2019. You don't have long to wait. Hang in there bro, we're all gonna make it.
Daniel Evans
t defeatist
Jacob Garcia
how many millions will this cost?
Adrian Robinson
only millions of yen i hope
Adam Bell
a million yen is $9,100... I am ok with this, but $25k is really as far as i can go, please make it cheap dr tusji
Justin Anderson
>tfw these threads started appearing 7 years ago
Hairlets...stop coping, it's never gonna happen...Just move on.
Connor Perry
>regenerate fully functional hair follicles and teeth >regenerate fully functional teeth >regenerate teeth >regenerate one of the costliest parts of the body to have upkept and fixed Jow Forums, the bunch of insecure fags that they are focuses on hair.
Which only makes sense since snake oil was invented. Then you faggets bitch why you have ED and your teeth fell out and uncle Sam didn't let you know it would happen
Fuck hair, I always had plenty of that. But I need new teeth.
Connor Brown
It's worse than that I'm afraid, we're going to see a hair density arms race. 18-year-olds with perfect hairlines are going to get their hair supercharged. We're going to see hair like we've never fucking seen before.
James Mitchell
>2018 >not teethmaxxing
not gonna make it
Luis Nelson
I've seen this article about 5 times in the past 2 months. Until it's actually being used it's BS.
Luis Carter
This is bad because hairlets are going to breed more and in the future the only way to get hair will be paying Hashima Hirostein.
What will you say in 2 years when it's available? Stop the damage control. Your days are numbered.
Tyler Gutierrez
made me laff
Blake Wright
In 2 years if it's available no one will be able to afford the procedure anyways, let alone the flight to and from Japan and all the days off of work that would require.
Kayden Price
thank you regrow ratto
Logan Howard
a flight from Los Angeles to Japan costs less than a thousand dollars; you can stay in a reasonable hotel in Tokyo for $250 a day; the surgery itself is probably going to be about the same price as existing surgeries (about $20k) because although there will be more grafts to insert, there will be no harvesting phase. The only unknown factor is the cost of the cellular processing. If they can't get it into the low tens of thousands (at most) of dollars, they wouldn't move to commercialise it so fast.
Easton Wright
>a flight from Los Angeles to Japan costs less than a thousand dollars And then you have to fly back. Most people don't live in LA to begin with so they'll have to fly/drive there or fly directly to Japan from where they currently are. >guesstimating about $20k I know I exaggerated when I said "no one", but this is going to price out the vast majority of potential customers.
Jason Evans
Fine. A RETURN flight from London, UK (about as far as you can get from Tokyo) is £460 ($630).
And $20k is nothing to pay for permanent, life-long hair. Consider that financing will be available, just as it is for existing hair transplants which don't work so well. You can already pay in instalments over terms as long as 10 years, with interest rates of 5-20% depending on your credit, with deposits in the mid single digits (e.g. $5k).
James Wood
What does an anonymous poster with a head full of hair have to lose in this argument? How would his days be numbered? What does he even lose if you gain hair? You sound like a fuckin' movie villain.
Austin Nguyen
> What does an anonymous poster with a head full of hair have to lose in this argument? An advantage.
Angel Stewart
You will have to complete with the flood of ex-baldy Chads again. If you already have a full head of hair this development can only bring you down.
Lucas James
*compete *ex-bald fuck me lads
Nicholas Lee
Spotted the brainlet.
Charles Kelly
Thank you regrowth ratto
Camden Bennett
thank you regrowth ratto - you are my favorite rat
Adam Robinson
thank you regrow ratto
Ryan Clark
thank you regrow ratto
Hudson Taylor
The madman actually did it. BASED TSUJI.
Henry Wilson
this is all cope
Luis Phillips
On what basis do you just dismiss all of the scientific papers and clear statements of the researchers provided above?
Dominic Green
This.
Reminder to sage these threads.
You cannot change genetics.
James Bell
thank you regrow ratto, lend me your power!
Aaron Brown
Thank you regrow ratto
Daniel Williams
thank you regrow ratto
Robert James
who cares about hair, give me teeth
Jacob Price
thank you regrow ratto
Aiden Cox
Thank you, regrow ratto
Xavier Gonzalez
By the time this happens I will be forty and it will all be for naught.
Jose Bailey
source?
Ayden Parker
Think of it this way. Even if this shit isn't commercially practical for anyone below the 95th percentile earners for 20 years, at least it means there's a long-term solution in the works. This means that if you do start taking fin or getting holding action hair plugs now, by the time they're getting thin and gross again in another 10-15-20 years, there will be a better, more permanent solution on the market. Shit, maybe this means that normal hair transplants will finally get cheaper.
This shit will always be a vanity procedure for the elite and well-off. Hair is ultimately just an aesthetic feature of the modern human, so these people can charge whatever they want for a luxury treatment.
Also who knows what kind of bizarre health complications will be associated with the first generation of this technology.
I see this has been getting spammed on Jow Forums for a while now, no source then?
Ian Turner
Because is japanese ? are you that scared, american ?
Jeremiah Sanders
can you repeat that in English?
Jacob Hall
thank you regrow ratto
Angel Hughes
thank you regrow ratto
Dylan Butler
Shit you're right. I'm hype now for a full head of nosehair.
Benjamin Lee
At this stage I'm more interested in shit like Medipost, RiverTown and the shit Jing Huang is doing at UCLA. Topical, nonsurgical solutions are much more accessible and much easier to get approved and set up by pharma than a weird cell culture operation.
Either way, it looks like balding will be mostly treatable within our lifetimes. The only question is if we'll be able to take advantage of it by then, or if we'll be looking like Hulk Hogan for a while first.
Jow Forums here, are any of these companies publicly traded? There's going to be a massive demand for the product that reliably stops or reverses hair loss, and we should try to get on that boat as soon as we can.
