Is insulin a meme...

Carbs are only a problem if you already fucked your insulin sensitivity. Basically, if you've always been healthy, you can really just eat what you want and only worry about total calorie count. If you're pre-diabetic, you should avoid all sugars, and if you got full blown beetus, you can't really have carbs at all.

Protein only spikes insulin when eaten with carbs.

care.diabetesjournals.org/content/38/7/e98?sid=ea6d4bd4-98f6-4347-9238-15e2a4c019db

>if you've always been healthy, you can really just eat what you want and only worry about total calorie count.
Imagine being dumb enough to count calories.

Okay, how is the hormone model compatible with basic physics, i.e. every action needs energy, energy can't be created nor destroyed?

lol no
>"A stimulatory effect on insulin release from isolated islets was observed with serum after whey obtained at 15 min (+87%, P < 0.05) and 30 min (+139%, P < 0.05) postprandially, compared with control serum. The combination of isoleucine, leucine, valine, lysine and threonine exerted strong stimulatory effect on insulin secretion (+270%, P < 0.05), which was further augmented by GIP (+558% compared to that produced by glucose, P < 0.05)."
ncbi.nlm.nih.gov/pubmed/22647249

IM A MEDFAG LISTEN YOU NIGGAS

TO BURN FAAT YOU NEED enzyme "lipase" which is inactivated by insulin!!!!
so is your insulin low -> lipase is active -> and lipase will "burn" your fat -> so fat turns into Acetyl CoA and the power house of the cell turns this acetyl coa into ketoacids. the cell can use keto acids as an alternative energy -> so the fat is burned!!!!

Tldr: kaka poo poo

Acetyl CoA isn't turned to ketoacids in the mitochondria, it just goes through the Krebs Cycle and is burned, like carbs and protein after turning into Acetyl CoA.
Only the liver creates ketones, and only if beta oxidation is not possible. Mitochondria turn them back into acetyl CoA and do the regular Krebs cycle.

>How is flight compatible with basic physics, i.e. gravity?

Attached: brainlet.jpg (645x729, 48K)

Fat is lost simply because most diets are only 2 to 3 meals anyway. Furthermore, protein is suggested in amounts about 100 - 150g / day (especially because it's the second most abundant item in the body, to water; and intakes are what's most scientifically correlated to height).

Nutrient timing and availability are really important.

Attached: Benefits - Casein vs. Whey.png (1054x600, 133K)

I'm a MD and never take something who make you loose fat by resting.

this is kind of right what you wrote there.
but when your insulin is low the krebs cycle can be inactivated which forces the liver to produce ketoacids.

Lift is a force created by the shape of wings and the flow of air around them that opposes the force of gravity.

Now you tell me where the energy for your organs working and your body moving comes from as well as the fat that you're apparently adding while also not burning fat and not adding enough energy in the form of food to your body to meet the needs. Last I checked we are not capable of photosynthesis.

This isn't due to low insulin but because gluconeogenesis is eating up all the liver's oxaloacetate, making the liver incapable of burning fat for energy past the Acetyl CoA stage.

Actually kind of ironic given people believe high insulin stops you from burning fat.

wat

Flight is perfectly compatible with gravity, lift overcomes gravity and an object can fly.

If a body needs 2500kcal per day to maintain bodyweight, and it only recieves 2000kcal, it must pull energy from tissue or lower the metabolism to obey the laws of physics.

yes, lack of insuline inhibates citrat synthase -> no citrat cyclus. -> forces liver to produce keto acids.

>2019
>not making sick sun gains

>Actually kind of ironic given people believe high insulin stops you from burning fat.

insuline blocks hormon sensitive Lipase -> so yes. insuline will stop you from burning fat.

Just look up "what I've learned" on YouTube and you'll learn everything you need.

>ketotards
le every time

It will reduce the rate at which fat is utilized depending on concentration. Because higher insulin = more nutrients already in your blood stream that need to get into the cells like "hey we don't need that much right now". But there's very few if any things in your body that will outright stop another process completely. You're always in a flux of storing and releasing nutrients into and out of cells to fit your needs.

Doctor here. Insulin is not a meme. Insulin does not make you fat. Insulin is simply the primary anabolic hormone in the fed state. It promotes protein synthesis, glycogen storage, cellular metabolism in general. It’s opposed by glucagon which promotes protein (primarily in the muscles). Breakdown, mobilization of fat stores and glucose production in the liver.

Insulin predominates in the fed state after meals when elevated serum glucose triggers the release of insulin from the beta cells of the pancreas. Insulin also inhibits glucagon release. Thus when blood sugar is low I.e. the fasting state, Insulin is low, it can’t inhibit glucagon release and thus glucagon is secreted to raise blood sugar. Glucagon works in concert with cortisol to help the body respond to stress. Cortisol itself causes cells to be resistant to the insulin signal and be less efficient at taking up sugar.

So know, it’s not a meme.

>after ingestion of carbohydrate equivalent meals
Holy fuck youre stupid. Stop posting.

Nothing about the hormonal theory of obesity violates the laws of physics.

this is putting the cart before the horse. Insulin isn't the prime mover, merely a mediator. If you're in a calorically-deficient state, your insulin will naturally be low as you motivate your fat, glycogen, etc. stores.

bingo

It's wrong because it implies high insulin causes obesity. Which is incorrect. Caloric surplus which is the ultimate cause of obesity causes insulin to be high in order for your body to be able to put the shit floating in your blood into your cells and drive anabolic processes.

Wrong.

Insulin causes obesity.

I cut on low fat, high protein, high carb.

Calories in vs calories out. Carbs don't make you fat on their own, lipogenesis from carbs is a costly process, it's not going to happen unless you're at a severe surplus.

Look up the Randle cycle. Don't eat carbs and fat at the same time, the insulin spike sends the fat straight into your fat cells.

You shouldn't be concerned with insulin unless you're a contest bodybuilder or a diabetic.

In conclusion:
For the average dyel, 14-20%bf, not diabetic,gym goerm counting (most) calories and macros and eating (mostly) clean:
- Eat at a moderate (500kcal) deficit when cutting, thent at a moderate (300kcal) surplus the rest of the time.
- Protein target next (0.7-1.2g/lb body mass)
- Fat next (0.3-0.5g/lb body mass)
- Fiber next (+16g/1000kcal intake)
- Fill the rest with carb
- Meal timing doesn't matter except some carbs pre/post workout
- Protein timing doesn't matter much but evenly spaced (+20g/each) between 4-6 meals is better
- Forget about gluconeogenesis, lipogenesis, beta oxidation, ketosis, insulin, HGH, IFG-1, etc. CICO will determine weight change, training and protein will determine if muscle mass will be preserved (on deficit) or increases (on surplus)

>Look up the Randle cycle. Don't eat carbs and fat at the same time, the insulin spike sends the fat straight into your fat cells.
Can I lose fat eating burgers then?

Yes. Look up Cole's video where he spends an entire month eating only McDonalds burgers and salads and loses some fat and maintains good health the entire time.

because they count calories, which is a very unoptimal way of losing fat.
cico works, but its not efficient.

>If you're in a calorically-deficient state, your insulin will naturally be low as you motivate your fat, glycogen, etc. stores.
this. medical studies have shown that a low-carbohydrate diet is equal to a high-crab diet in terms of losing weight.

>if total catabolism > anabolism, fat will be lost

Bullshit. Energy will be lost. Or maybe energy expenditure (BMI) will fall and you will feel cold and tired and cannot think.

Or maybe you will be like that breed of rats that literally die from starvation while still obese because they cannot mobilize fat from fat cells.

CICO is full retard.

Attached: full_retard.jpg (750x600, 82K)

They are both in the causal chain but

1. Many people, if they eat carbs frequently, have a hormone setup that makes if hard/impossible to burn fat. So when they diet they a) feel cold and tired b) cannot think c) feel ravenously hungry.

2. Calories in / out are not independent inputs to the system for such people. They are effects more than causes.

3. It is true that after a few days low carb or fasting, insulin will generally fall and allow fat to be burned.

I personally experienced this. On a low fat / high carb diet I could not lose fat. When I dieted I felt tired and cold and hungry and could not think.

On low carb I lose fast effortlessly.

One way to think of this is in terms of Donella Meadows "levels of intervention in a system". CICO is a very low level intervention. It is like stopping subway overcrowding by stopping people from getting onto the train.

Or explaining why someone is poor by "spent more than they earned". They are shallow explanations and remedies that often fail to deal with the real problem.

donellameadows.org/archives/leverage-points-places-to-intervene-in-a-system/

Attached: dieting_you_are_doing_it_wrong_1303337850948.jpg (500x375, 37K)

What is physical fatigue for 300?

I'm too dumb to read this thread, or anything for that matter,but can someone reply to this post and let me know if we decided whether insulin was a meme or not? I'm leaning towards yes, but I just don't know.

There are at least 31 modern scientific studies of the highest quality (RCTs, or randomized controlled trials) that show significantly better weight loss with low-carb diets.
phcuk.org/rcts/

Attached: PHC-LC-v-LF-RCTs-Inforgraphic-26.02.2018.png (805x571, 34K)

As a general rule, all biological processes are considered to be happening in the body simultaneously. Some just at a much higher proportion than others. Insulin greatly hampers fat burning (or rather, amps up fat storage) but it's not binary.

There's two type of people.

1. People who agree with the hormonal theory of obesity.
2. Lying shills who want you to believe Coca-Cola can be part of a healthy diet.

Of course CICO is the only thing that matters for weight loss at the core, but energy availability can affect the CO part

for a retard someone please help me, the maths and abbreviations make it impossible for me to understand. Is this saying casein is better or worse than whey?

The carbohydrate-insulin model of obesity already has been falsified. That is, with constant calorie intake, no macro ratio directly affects the amount of fat burned. It may affect satiety and therefore how much cake you are prone to stuffing into your bottomless maw, but CICO reigns supreme.
The positive effects of keto only work on the 6 month scale, by 1 year they disappear, hence why user above didn't include most of the longer studies in his count of one that support it (if I recall correctly - I don't have time to double check right now).

>zero carb says highfat
Shawn baker suggests otherwise

Stop lying.

>Insulin reduces mitochondrial uncoupling
ncbi.nlm.nih.gov/pubmed/29170160

Then why is low carb matching other types of diet at the 1 year mark? It should be ahead consistently, forever. The longer studies in your own link show this.

Please, stop lying.

Low carb does not just result in more weight loss than other comparison diets, it also results in more fat loss, especially when carbs are limited to 50 grams per day:
ncbi.nlm.nih.gov/pubmed/27059106

Where did you get your phd? Broville?

Not on people who already fucked their insulin sensitivity. You need to keep in mind that keto people started to lose weight when they couldn't manage to do it with anything else for years, so most of them are damn near diabetic, and carbs really are the devil for them.

casein better.

define weight loss
fat loss is the same when protein intake is equalled
so there is no benefit, at all

>ncbi.nlm.nih.gov/pubmed/27059106
>no protein consideration
garbage
protein is the one macro that grants benefit, it's not the high fat or the low carb, it's the high protein you fucking imbecile, and it just so happens that "keto" low carb diets are almost exclusively higher in protein

Your body burns fat all day every day unless eating very-high carb diet, in which case you will briefly burn 100% carbs after meals, but not in between. Obese people burn more fat than normalweight people, so there is no metabolic reason for their obesity, quite the opposite

In "That sugar film" a guy eats the exact same amount of calories but makes a higher percentage of his calories come from fructose. Within 16 days he develops fatty liver disease and within 30 days he gets a soda gut. How does calories in < calories out explain this?

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You have to keep insulin steady that means low glycemic value carbs with every meal in a consistent amount that keeps your blood sugar steady throughout the day
You can easily cut on high carbs if you keep overall calories below maintenance, just eat proper food and not empty carbs

the leaner the protein the higher the spike , something as whey spikes it quite high and then combine with shit tier whey that has added sugar

he turned from Benedict Cumberbatch to Johnny Knoxville

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Yeah, but as a burger AND burger lover you'll eventually lose yer affection for them while suffering a existential crisis. Moderation makes the best spice

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the 2300 number could have been wrong in the first place

>fatty liver disease and gut from a few extra calories
nah

>unga bunga
>NO
>*gives zero explanation because brainlet*

Look how stupid you are and you're trying to smart fight.

fructose composition makes it create fat, i agree cico is a stupid way to lose fat

there's TEF
you burn more calories digesting protein than carbs and fats, fats being the one's that burn fewer calories. And lifters usually consume high protein so it has a significant difference, yhou could be burning ~100kcals extra per day due to high protein
also carbs from fruit are different from potatoes, rice, etc. doesnt mean shit when you eat a balanced diet but if you just eat a shit ton of fruit everyday on a surplus then it's idfferent.

martin berkhan book goes through the TEF(thermic effect of food)

We should never have taught chimps how to use ncbi.

My god the fucking retardation ITT. Nutrition for weight composition was worked out decades ago.

Lots of protein, preferably 1g/lb of lean mass.
Moderate fats, maybe ~75g
Raise or lower carbs depending on if you're bulking or cutting.

The only recent knowledge is that timing meals appropriately can help you cut or gain.